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⭐ wikimedshop.com ⭐ Fioricet is a prescription medication that combines three active ingredients: acetaminophen, butalbital, and caffeine. This combination works synergistically to relieve headache symptoms. Acetaminophen is a pain reliever, butalbital is a barbiturate that helps relax the muscles and alleviate tension, while caffeine acts as a central nervous system stimulant that enhances the effects of the other ingredients.